Regulate the Chemicals is an album by indie rock band Twothirtyeight. The album was originally released in 2000 through Takehold Records. It was pressed on vinyl by the now-defunct BlessedKilling Records in 2001. When Twothirtyeight signed to Tooth & Nail Records, Regulate the Chemicals was re-released with the songs "The Sticks Are Woven In The Spokes" and "Les Wirth". Chris Carrabba contributed backing vocals on the album.
The album was re-released on vinyl in 2009 by Recession Records.