TTC4

TTC4
Identifiers
Aliases	TTC4, tetratricopeptide repeat domain 4, CNS1
External IDs	OMIM: 606753 MGI: 1919604 HomoloGene: 31249 GeneCards: TTC4
Gene location (Human) Chr. Chromosome 1 (human) Band 1p32.3 Start 54,715,861 bp End 54,742,657 bp
Gene location (Mouse) Chr. Chromosome 4 (mouse) Band 4|4 C7 Start 106,519,453 bp End 106,536,141 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gastrocnemius muscle islet of Langerhans skeletal muscle tissue pituitary gland anterior pituitary left ventricle hypothalamus caudate nucleus Brodmann area 9 smooth muscle tissue Top expressed in spermatocyte spermatid seminiferous tubule neural tube superior frontal gyrus cerebellar cortex triceps brachii muscle maxillary prominence proximal tubule sternocleidomastoid muscle More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 7268 72354 Ensembl ENSG00000243725 ENSMUSG00000025413 UniProt O95801 Q8R3H9 RefSeq (mRNA) NM_004623 NM_001291333 NM_001172073 NM_028209 RefSeq (protein) NP_001278262 NP_004614 NP_001165544 NP_082485 Location (UCSC) Chr 1: 54.72 – 54.74 Mb Chr 4: 106.52 – 106.54 Mb PubMed search
Wikidata
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Tetratricopeptide repeat protein 4 is a protein that in humans is encoded by the TTC4 gene.

The 34-amino acid tetratricopeptide repeat (TPR) motif is found in a variety of proteins and may mediate protein-protein or protein-membrane interactions.[supplied by OMIM]

Further reading

• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Lan S, Wang H, Jiang H, et al. (2003). "Direct interaction between alpha-actinin and hepatitis C virus NS5B". FEBS Lett. 554 (3): 289–94. doi:10.1016/S0014-5793(03)01163-3. PMID 14623081.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Hey Y, Brintnell B, James LA, Varley JM (2000). "Assignment of TTC4 to human chromosome band 1p31.3 and a pseudogene TTC4P to 7p14→p13 by in situ hybridization". Cytogenet. Cell Genet. 88 (3–4): 272–4. doi:10.1159/000015536. PMID 10828607. S2CID 34754868.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.