PLSCR2

PLSCR2
Identifiers
Aliases	PLSCR2, phospholipid scramblase 2
External IDs	OMIM: 607610 HomoloGene: 124471 GeneCards: PLSCR2
Gene location (Human) Chr. Chromosome 3 (human) Band 3q24 Start 146,391,421 bp End 146,495,991 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sperm monocyte islet of Langerhans body of pancreas gallbladder rectum left uterine tube kidney right uterine tube appendix n/a More reference expression data BioGPS n/a
Gene ontology Molecular function phospholipid scramblase activity calcium ion binding metal ion binding Cellular component integral component of membrane plasma membrane membrane nucleus Biological process plasma membrane phospholipid scrambling Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 57047 n/a Ensembl ENSG00000163746 n/a UniProt Q9NRY7 n/a RefSeq (mRNA) NM_001199978 NM_001199979 NM_020359 n/a RefSeq (protein) NP_001186907 NP_001186908 NP_065092 n/a Location (UCSC) Chr 3: 146.39 – 146.5 Mb n/a PubMed search n/a
Wikidata
View/Edit Human

Phospholipid scramblase 2, also known as Ca²⁺-dependent phospholipid scramblase 2, is a protein that in humans is encoded by the PLSCR2 gene.

See also

• scramblase

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Sahu SK, Aradhyam GK, Gummadi SN (2009). "Calcium binding studies of peptides of human phospholipid scramblases 1 to 4 suggest that scramblases are new class of calcium binding proteins in the cell". Biochim. Biophys. Acta. 1790 (10): 1274–81. doi:10.1016/j.bbagen.2009.06.008. PMID 19540310.
• Yu A, McMaster CR, Byers DM, et al. (2003). "Stimulation of phosphatidylserine biosynthesis and facilitation of UV-induced apoptosis in Chinese hamster ovary cells overexpressing phospholipid scramblase 1". J. Biol. Chem. 278 (11): 9706–14. doi:10.1074/jbc.M204614200. PMID 12509439.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.