DENND4A

DENND4A
Available structures PDB Human UniProt search: PDBe RCSB List of PDB id codes 2PSN, 3B97
Identifiers
Aliases	DENND4A, IRLB, MYCPBP, DENN domain containing 4A
External IDs	OMIM: 600382 MGI: 2142979 HomoloGene: 55933 GeneCards: DENND4A
Gene location (Human) Chr. Chromosome 15 (human) Band 15q22.31 Start 65,658,046 bp End 65,792,293 bp
Gene location (Mouse) Chr. Chromosome 9 (mouse) Band 9|9 C Start 64,718,622 bp End 64,826,949 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon body of pancreas cerebellar hemisphere sural nerve right lobe of liver islet of Langerhans anterior pituitary monocyte bone marrow right lung Top expressed in substantia nigra bone marrow right lobe of liver spleen blood pineal gland piriform cortex otolith organ utricle primary motor cortex More reference expression data BioGPS More reference expression data
Gene ontology Molecular function DNA binding guanyl-nucleotide exchange factor activity protein binding Cellular component nucleus cytosol Biological process regulation of transcription, DNA-templated transcription, DNA-templated Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10260 102442 Ensembl ENSG00000174485 ENSMUSG00000053641 UniProt Q7Z401 n/a RefSeq (mRNA) NM_001144823 NM_005848 NM_001320835 NM_001376919 NM_001376920 NM_001162917 NM_176935 RefSeq (protein) NP_001138295 NP_001307764 NP_005839 NP_001363848 NP_001363849 n/a Location (UCSC) Chr 15: 65.66 – 65.79 Mb Chr 9: 64.72 – 64.83 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

C-myc promoter-binding protein is a protein that in humans is encoded by the DENND4A gene.

Further reading

• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization" (PDF). Curr. Biol. 14 (16): 1436–50. Bibcode:2004CBio...14.1436J. doi:10.1016/j.cub.2004.07.051. PMID 15324660. S2CID 2371325.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Uramoto H, Izumi H, Ise T, et al. (2002). "p73 Interacts with c-Myc to regulate Y-box-binding protein-1 expression". J. Biol. Chem. 277 (35): 31694–702. doi:10.1074/jbc.M200266200. PMID 12080043.

External links

• DENND4A human gene location in the UCSC Genome Browser.
• DENND4A human gene details in the UCSC Genome Browser.