MXRA7

MXRA7
Identifiers
Aliases	MXRA7, matrix remodeling associated 7
External IDs	HomoloGene: 134006 GeneCards: MXRA7
Gene location (Human)
Chr.	Chromosome 17 (human)
End	76,711,004 bp
RNA expression pattern
	Top expressed in
	saphenous vein; ; retinal pigment epithelium; ; urethra; ; vena cava; ; seminal vesicula; ; synovial joint; ; external globus pallidus; ; optic nerve; ; right ventricle; ; olfactory bulb;
	n/a
	More reference expression data
	n/a
Orthologs
	439921
	n/a
	ENSG00000182534
	n/a
	P84157
	n/a
NM_001008528; NM_001008529; NM_198530; NM_001363769; NM_001387276;
	NM_001387277; NM_001387278
	n/a
	NP_001008528; NP_001008529; NP_940932; NP_001350698
	n/a
	Wikidata
View/Edit Human

Matrix remodeling associated 7 is a protein that in humans is encoded by the MXRA7 gene found on chromosome 17. ^[3] Loss-of-function studies performed in MXRA7-deficient mice,^[4]^[5]^[6] in line with other types of data^[7]^[8]^[9]^[10] suggested that this gene was involved in multiple physiological or pathological processes.^[11]

References[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000182534 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Matrix remodeling associated 7". Retrieved 2019-08-06.
^ Zhou Z, Shen Y, Yin J, Xi F, Xu R, Lin D, et al. (August 2019). "Matrix remodeling associated 7 promotes differentiation of bone marrow mesenchymal stem cells toward osteoblasts". Journal of Cellular Physiology. 234 (10): 18053–18064. doi:10.1002/jcp.28438. PMID 30843215. S2CID 73475103.
^ Ning J, Shen Y, Wang T, Wang M, Liu W, Sun Y, et al. (September 2018). "Altered expression of matrix remodelling associated 7 (MXRA7) in psoriatic epidermis: Evidence for a protective role in the psoriasis imiquimod mouse model". Experimental Dermatology. 27 (9): 1038–1042. doi:10.1111/exd.13687. PMID 29781547. S2CID 29152069.
^ Lin D, Sun Z, Jin Z, Lei L, Liu Y, Hu B, et al. (2018). "Matrix Remodeling Associated 7 Deficiency Alleviates Carbon Tetrachloride-Induced Acute Liver Injury in Mice". Frontiers in Immunology. 9: 773. doi:10.3389/fimmu.2018.00773. PMC 5915751. PMID 29720975.
^ Jia C, Zhang F, Zhu Y, Qi X, Wang Y (October 2017). "Public data mining plus domestic experimental study defined involvement of the old-yet-uncharacterized gene matrix-remodeling associated 7 (MXRA7) in physiopathology of the eye". Gene. 632: 43–49. doi:10.1016/j.gene.2017.08.018. PMID 28847716.
^ Long NP, Park S, Anh NH, Min JE, Yoon SJ, Kim HM, et al. (January 2019). "Efficacy of Integrating a Novel 16-Gene Biomarker Panel and Intelligence Classifiers for Differential Diagnosis of Rheumatoid Arthritis and Osteoarthritis". Journal of Clinical Medicine. 8 (1): 50. doi:10.3390/jcm8010050. PMC 6352223. PMID 30621359.
^ Veiga-Castelli LC, Silva JC, Meola J, Ferriani RA, Yoshimoto M, Santos SA, et al. (August 2010). "Genomic alterations detected by comparative genomic hybridization in ovarian endometriomas". Brazilian Journal of Medical and Biological Research. 43 (8): 799–805. doi:10.1590/s0100-879x2010007500072. PMID 20725696.
^ Wang M, Shen Y, Li Y, Wang Y (2019). "Potential Partners of Matrix-Remodeling Associated 7 (MXRA7) in Murine Liver". Chinese Journal of Biochemistry and Molecular Biology. 35 (1): 51–66.
^ Wang Y (2020). "Matrix Remodeling Associated 7 (MXRA7): a Long-lost Member of the Non-kin MXRA Family". Chinese Journal of Biochemistry and Molecular Biology. 36 (7): 725–733. doi:10.13865/j.cnki.cjbmb.2020.06.1130.

This article on a gene on human chromosome 17 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000182534 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-3] "Entrez Gene: Matrix remodeling associated 7". Retrieved 2019-08-06.

[pmid30843215-4] Zhou Z, Shen Y, Yin J, Xi F, Xu R, Lin D, et al. (August 2019). "Matrix remodeling associated 7 promotes differentiation of bone marrow mesenchymal stem cells toward osteoblasts". Journal of Cellular Physiology. 234 (10): 18053–18064. doi:10.1002/jcp.28438. PMID 30843215. S2CID 73475103.

[pmid29781547-5] Ning J, Shen Y, Wang T, Wang M, Liu W, Sun Y, et al. (September 2018). "Altered expression of matrix remodelling associated 7 (MXRA7) in psoriatic epidermis: Evidence for a protective role in the psoriasis imiquimod mouse model". Experimental Dermatology. 27 (9): 1038–1042. doi:10.1111/exd.13687. PMID 29781547. S2CID 29152069.

[pmid29720975-6] Lin D, Sun Z, Jin Z, Lei L, Liu Y, Hu B, et al. (2018). "Matrix Remodeling Associated 7 Deficiency Alleviates Carbon Tetrachloride-Induced Acute Liver Injury in Mice". Frontiers in Immunology. 9: 773. doi:10.3389/fimmu.2018.00773. PMC 5915751. PMID 29720975.

[pmid28847716-7] Jia C, Zhang F, Zhu Y, Qi X, Wang Y (October 2017). "Public data mining plus domestic experimental study defined involvement of the old-yet-uncharacterized gene matrix-remodeling associated 7 (MXRA7) in physiopathology of the eye". Gene. 632: 43–49. doi:10.1016/j.gene.2017.08.018. PMID 28847716.

[pmid30621359-8] Long NP, Park S, Anh NH, Min JE, Yoon SJ, Kim HM, et al. (January 2019). "Efficacy of Integrating a Novel 16-Gene Biomarker Panel and Intelligence Classifiers for Differential Diagnosis of Rheumatoid Arthritis and Osteoarthritis". Journal of Clinical Medicine. 8 (1): 50. doi:10.3390/jcm8010050. PMC 6352223. PMID 30621359.

[pmid20725696-9] Veiga-Castelli LC, Silva JC, Meola J, Ferriani RA, Yoshimoto M, Santos SA, et al. (August 2010). "Genomic alterations detected by comparative genomic hybridization in ovarian endometriomas". Brazilian Journal of Medical and Biological Research. 43 (8): 799–805. doi:10.1590/s0100-879x2010007500072. PMID 20725696.

[10] Wang M, Shen Y, Li Y, Wang Y (2019). "Potential Partners of Matrix-Remodeling Associated 7 (MXRA7) in Murine Liver". Chinese Journal of Biochemistry and Molecular Biology. 35 (1): 51–66.

[11] Wang Y (2020). "Matrix Remodeling Associated 7 (MXRA7): a Long-lost Member of the Non-kin MXRA Family". Chinese Journal of Biochemistry and Molecular Biology. 36 (7): 725–733. doi:10.13865/j.cnki.cjbmb.2020.06.1130.

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