INTS7

INTS7
Identifiers
Aliases	INTS7, C1orf73, INT7, integrator complex subunit 7
External IDs	OMIM: 611350 MGI: 1924315 HomoloGene: 9136 GeneCards: INTS7
Gene location (Human)
Chr.	Chromosome 1 (human)
End	212,035,557 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	191,355,800 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; sperm; ; islet of Langerhans; ; right lobe of liver; ; oocyte; ; secondary oocyte; ; rectum; ; endothelial cell; ; stromal cell of endometrium; ; monocyte;
	Top expressed in
	cumulus cell; ; primitive streak; ; endocardial cushion; ; maxillary prominence; ; hair follicle; ; spermatocyte; ; medial ganglionic eminence; ; ureter; ; medullary collecting duct; ; dermis;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	integrator complex; chromosome; nucleoplasm; nucleus; cytoplasm; nuclear body;
Biological process	cellular response to ionizing radiation; DNA damage checkpoint signaling; snRNA processing; cellular response to DNA damage stimulus; snRNA transcription by RNA polymerase II; snRNA 3'-end processing;
	Sources:Amigo / QuickGO
Orthologs
	25896
	77065
	ENSG00000143493
	ENSMUSG00000037461
	Q9NVH2
	Q7TQK1
	NM_001199809; NM_001199811; NM_001199812; NM_015434
	NM_178632; NM_001306203; NM_001306204
	NP_001186738; NP_001186740; NP_001186741; NP_056249
	NP_001293132; NP_001293133; NP_848747
	Wikidata
View/Edit Human	View/Edit Mouse

Integrator complex subunit 7 is a protein that in humans is encoded by the INTS7 gene.^[5]^[6]

References[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000143493 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000037461 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Baillat D, Hakimi MA, Naar AM, Shilatifard A, Cooch N, Shiekhattar R (Oct 2005). "Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II". Cell. 123 (2): 265–76. doi:10.1016/j.cell.2005.08.019. PMID 16239144. S2CID 18069461.
^ "Entrez Gene: INTS7 integrator complex subunit 7".

Further reading[edit]

Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000143493 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000037461 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid16239144-5] Baillat D, Hakimi MA, Naar AM, Shilatifard A, Cooch N, Shiekhattar R (Oct 2005). "Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II". Cell. 123 (2): 265–76. doi:10.1016/j.cell.2005.08.019. PMID 16239144. S2CID 18069461.

[entrez-6] "Entrez Gene: INTS7 integrator complex subunit 7".

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