CRISP2

CRISP2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2CQ7
Identifiers
Aliases	CRISP2, CRISP-2, CT36, GAPDL5, TPX1, TSP1, cysteine rich secretory protein 2
External IDs	OMIM: 187430 MGI: 98815 HomoloGene: 37756 GeneCards: CRISP2
Gene location (Human)
Chr.	Chromosome 6 (human)
End	49,713,590 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	41,117,894 bp
RNA expression pattern
	Top expressed in
	sperm; ; right uterine tube; ; pancreatic ductal cell; ; bronchial epithelial cell; ; minor salivary glands; ; caput epididymis; ; gallbladder; ; bone marrow; ; trabecular bone; ; seminal vesicula;
	Top expressed in
	seminiferous tubule; ; spermatid; ; spermatocyte; ; muscle tissue; ; white adipose tissue; ; islet of Langerhans; ; striated muscle tissue; ; skeletal muscle tissue; ; piriform cortex; ; entorhinal cortex;
	More reference expression data
	More reference expression data
Orthologs
	7180
	22024
	ENSG00000124490
	ENSMUSG00000023930
	P16562
	P16563
NM_001142407; NM_001142408; NM_001142417; NM_001142435; NM_001261822;
	NM_003296
	NM_001204071; NM_009420
NP_001135879; NP_001135880; NP_001135889; NP_001135907; NP_001248751;
	NP_003287
	NP_001191000; NP_033446
	Wikidata
View/Edit Human	View/Edit Mouse

Cysteine-rich secretory protein 2 is a cysteine-rich secretory protein that in humans is encoded by the CRISP2 gene.^[5]^[6]^[7]

References[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000124490 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000023930 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kasahara M, Gutknecht J, Brew K, Spurr N, Goodfellow PN (Mar 1990). "Cloning and mapping of a testis-specific gene with sequence similarity to a sperm-coating glycoprotein gene". Genomics. 5 (3): 527–34. doi:10.1016/0888-7543(89)90019-0. PMID 2613236.
^ Kratzschmar J, Haendler B, Eberspaecher U, Roosterman D, Donner P, Schleuning WD (Aug 1996). "The human cysteine-rich secretory protein (CRISP) family. Primary structure and tissue distribution of CRISP-1, CRISP-2 and CRISP-3". Eur J Biochem. 236 (3): 827–36. doi:10.1111/j.1432-1033.1996.t01-1-00827.x. PMID 8665901.
^ "Entrez Gene: CRISP2 cysteine-rich secretory protein 2".

External links[edit]

Human CRISP2 genome location and CRISP2 gene details page in the UCSC Genome Browser.

Further reading[edit]

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Busso D, Cohen DJ, Hayashi M, et al. (2005). "Human testicular protein TPX1/CRISP-2: localization in spermatozoa, fate after capacitation and relevance for gamete interaction". Mol. Hum. Reprod. 11 (4): 299–305. doi:10.1093/molehr/gah156. hdl:11336/31466. PMID 15734896.
Du Y, Huang X, Li J, et al. (2006). "Human testis specific protein 1 expression in human spermatogenesis and involvement in the pathogenesis of male infertility". Fertil. Steril. 85 (6): 1852–4. doi:10.1016/j.fertnstert.2005.11.064. PMID 16759931.

This article on a gene on human chromosome 6 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000124490 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000023930 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid2613236-5] Kasahara M, Gutknecht J, Brew K, Spurr N, Goodfellow PN (Mar 1990). "Cloning and mapping of a testis-specific gene with sequence similarity to a sperm-coating glycoprotein gene". Genomics. 5 (3): 527–34. doi:10.1016/0888-7543(89)90019-0. PMID 2613236.

[pmid8665901-6] Kratzschmar J, Haendler B, Eberspaecher U, Roosterman D, Donner P, Schleuning WD (Aug 1996). "The human cysteine-rich secretory protein (CRISP) family. Primary structure and tissue distribution of CRISP-1, CRISP-2 and CRISP-3". Eur J Biochem. 236 (3): 827–36. doi:10.1111/j.1432-1033.1996.t01-1-00827.x. PMID 8665901.

[entrez-7] "Entrez Gene: CRISP2 cysteine-rich secretory protein 2".

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