Dragomabin

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Dragomabin
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
  • InChI=1S/C37H51N5O6/c1-9-10-11-13-16-25(2)35(45)42(7)32(24-28-17-14-12-15-18-28)34(44)39-26(3)36(46)40(5)27(4)37(47)41(6)31(33(38)43)23-29-19-21-30(48-8)22-20-29/h1,12,14-15,17-22,25-27,31-32H,10-11,13,16,23-24H2,2-8H3,(H2,38,43)(H,39,44)/t25-,26-,27-,31-,32-/m0/s1
    Key: JAYHQHZOWYDLDQ-PONGSQKHSA-N
  • InChI=1/C37H51N5O6/c1-9-10-11-13-16-25(2)35(45)42(7)32(24-28-17-14-12-15-18-28)34(44)39-26(3)36(46)40(5)27(4)37(47)41(6)31(33(38)43)23-29-19-21-30(48-8)22-20-29/h1,12,14-15,17-22,25-27,31-32H,10-11,13,16,23-24H2,2-8H3,(H2,38,43)(H,39,44)/t25-,26-,27-,31-,32-/m0/s1
    Key: JAYHQHZOWYDLDQ-PONGSQKHBM
  • C[C@@H](CCCCC#C)C(=O)N(C)[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N(C)[C@@H](C)C(=O)N(C)[C@@H](Cc2ccc(cc2)OC)C(=O)N
Properties
C37H51N5O6
Molar mass 661.831
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Dragomabin is a bio-active isolate of marine cyanobacteria, Lyngbya majuscula, which has been shown to have good antimalarial activity.[1]

References[edit]

  1. ^ McPhail, Kerry L.; Correa, Jhonny; Linington, Roger G.; González, José; Ortega-Barría, Eduardo; Capson, Todd L.; Gerwick, William H. (June 2007). "Antimalarial Linear Lipopeptides from a Panamanian Strain of the Marine Cyanobacterium". Journal of Natural Products. 70 (6): 984–988. doi:10.1021/np0700772. PMC 2745555. PMID 17441769.