MRM1 (gene)

MRM1
Identifiers
Aliases	MRM1, mitochondrial rRNA methyltransferase 1
External IDs	OMIM: 618099 MGI: 2443470 HomoloGene: 40307 GeneCards: MRM1
Gene location (Human) Chr. Chromosome 17 (human) Band 17q12 Start 36,601,583 bp End 36,608,964 bp
Gene location (Mouse) Chr. Chromosome 11 (mouse) Band 11|11 C Start 84,703,887 bp End 84,710,341 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in gastrocnemius muscle left ventricle right adrenal gland left adrenal gland right lobe of liver spleen skeletal muscle tissue lymph node duodenum body of pancreas Top expressed in interventricular septum extraocular muscle yolk sac right ventricle myocardium of ventricle cumulus cell aortic valve soleus muscle digastric muscle blood More reference expression data BioGPS n/a
Gene ontology Molecular function methyltransferase activity RNA methyltransferase activity transferase activity protein binding rRNA (guanosine-2'-O-)-methyltransferase activity RNA binding Cellular component mitochondrion mitochondrial matrix Biological process rRNA processing methylation RNA processing enzyme-directed rRNA 2'-O-methylation rRNA 2'-O-methylation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79922 217038 Ensembl ENSG00000274853 ENSG00000278619 ENSMUSG00000018405 UniProt Q6IN84 Q99J25 RefSeq (mRNA) NM_024864 NM_145433 RefSeq (protein) NP_079140 NP_663408 Location (UCSC) Chr 17: 36.6 – 36.61 Mb Chr 11: 84.7 – 84.71 Mb PubMed search
Wikidata
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Mitochondrial rRNA methyltransferase 1 is a protein that in humans is encoded by the MRM1 gene.

Further reading

• Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ (September 2010). "Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression". PLOS ONE. 5 (9): e12862. Bibcode:2010PLoSO...512862H. doi:10.1371/journal.pone.0012862. PMC 2943476. PMID 20877624.