Kristina Micheva

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Kristina Micheva
Photograph of a woman wearing a purple jumper, a blue headscarf, and glasses.
Micheva in 2021
Born
Sofia, Bulgaria
Known forInvention of Array Tomography
Academic background
EducationSofia University
University of Montreal
Academic work
DisciplineNeuroscience
InstitutionsStanford University

Dr Kristina Micheva is a Bulgarian-American neuroscientist[1] at Stanford University.[2] She is one of the inventors of Array Tomography, a technique in which proteins are detected with antibodies in ultra-thin sections of brain tissue using confocal microscopy.[3][4][5]

Education[edit]

Micheva was a biology major at the University of Sofia. She received a masters in plant ecology at the University of Sofia as well.[1] After graduation, she worked in a lab at a medical university in Sofia where she learned electron microscopy and how to work with brain sections.[6] She moved to Montreal, Quebec to pursue a PhD in neuroscience (receiving the degree in 1996).[6] In 1996 she participated in the Marine Biological Laboratory Neurobiology Course,[7] in which she later taught as faculty (2006-2014).[8]

Research[edit]

Micheva's main interest is in studying how brain structures develop and change with experience.[9] During her PhD, she studied how sensory experience affects cortical development.[9]

Invention of Array Tomography[edit]

Micheva co-developed the Array Tomography technique with Stephen J Smith. In this technique, proteins are detected with antibodies in ultra-thin sections of brain tissue using confocal microscopy.[10][5][3] This technique can be combined with electron microscopy and is the only technique that allows a voxel-conjugate joining of fluorescence and electron microscopy methods.[11] Given the advantages of this method, it is considered an excellent choice for challenging explorations of cellular architectures in mature and developing tissues.[11]

Personal life[edit]

In her free time, Micheva practices karate. She is a third-degree black belt as of the spring of 2021, and teaches a children's karate class.[12]

References[edit]

  1. ^ a b "Episode 02: Kristina Micheva, PhD". Conjugate: Illustration and Science Blog. Retrieved 2021-04-26.
  2. ^ "Kristina Micheva's Profile | Stanford Profiles". profiles.stanford.edu. Retrieved 2021-05-03.
  3. ^ a b "What is Immunofluorescent Array Tomography?". News-Medical.net. 2019-12-10. Retrieved 2021-05-02.
  4. ^ "Synapses on Stage". The Scientist Magazine®. Retrieved 2021-04-28.
  5. ^ a b Pastrana, Erika (January 2011). "Unraveling synapse diversity". Nature Methods. 8 (1): 16. doi:10.1038/nmeth0111-16. ISSN 1548-7105. S2CID 29464084.
  6. ^ a b "Episode 02: Kristina Micheva, PhD". Conjugate: Illustration and Science Blog. Retrieved 2021-04-27.
  7. ^ "Neurobiology 1996 (Course) | History of the Marine Biological Laboratory". amphora.asu.edu. Retrieved 2021-05-03.
  8. ^ "Kristina Micheva (Person) | History of the Marine Biological Laboratory". amphora.asu.edu. Retrieved 2021-05-03.
  9. ^ a b "Episode 02: Kristina Micheva, PhD". Conjugate: Illustration and Science Blog. Retrieved 2021-05-02.
  10. ^ "Touring Memory Lane Inside The Brain". NPR.org. Retrieved 2021-04-28.
  11. ^ a b Smith, Stephen J. (2018-09-06). "Q&A: Array tomography". BMC Biology. 16 (1): 98. doi:10.1186/s12915-018-0560-1. ISSN 1741-7007. PMC 6127925. PMID 30189863.
  12. ^ "Episode 02: Kristina Micheva, PhD". Conjugate: Illustration and Science Blog. Retrieved 2021-04-28.
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