DGCR5

DGCR5
Identifiers
Aliases	DGCR5, LINC00037, NCRNA00037, DiGeorge syndrome critical region gene 5 (non-protein coding), DiGeorge syndrome critical region gene 5
External IDs	OMIM: 618040 GeneCards: DGCR5
Gene location (Human)
Chr.	Chromosome 22 (human)
End	19,031,242 bp
RNA expression pattern
	Top expressed in
	prefrontal cortex; ; Brodmann area 9; ; nucleus accumbens; ; cingulate gyrus; ; amygdala; ; caudate nucleus; ; putamen; ; ganglionic eminence; ; hippocampus proper; ; anterior pituitary;
	n/a
	More reference expression data
	n/a
Orthologs
	26220
	n/a
	ENSG00000273032
	n/a
	n; a
	n/a
	n/a
	n/a
	n/a
	n/a
	Wikidata
View/Edit Human

In molecular biology, DiGeorge syndrome critical region gene 5 (non-protein coding), also known as DGCR5, is a long non-coding RNA. In humans, it is located on chromosome 22q11, at the ADU breakpoint associated with DiGeorge syndrome.^[3] Its expression is regulated by the transcription factor REST (RE1-Silencing Transcription factor).^[4]

References[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000273032 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Sutherland HF, Wadey R, McKie JM, Taylor C, Atif U, Johnstone KA, Halford S, Kim UJ, Goodship J, Baldini A, Scambler PJ (Jul 1996). "Identification of a novel transcript disrupted by a balanced translocation associated with DiGeorge syndrome". American Journal of Human Genetics. 59 (1): 23–31. PMC 1915101. PMID 8659529.
^ Johnson R, Teh CH, Jia H, Vanisri RR, Pandey T, Lu ZH, Buckley NJ, Stanton LW, Lipovich L (Jan 2009). "Regulation of neural macroRNAs by the transcriptional repressor REST". RNA. 15 (1): 85–96. doi:10.1261/rna.1127009. PMC 2612765. PMID 19050060.

DGCR5

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