Ephraim Levin
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Ephraim Y. Levin, (February 22, 1933, Baltimore, Maryland, - November 20, 2020) was an American scientist.[1][2]
Academic career[edit]
1957 BA and MA, 1953, MD, 1957 at Johns Hopkins University. He had an internship and residencies at Johns Hopkins Hospital and Sinai Hospital of Baltimore. He served in the United States Public Health Service USPHS from 1953 to 1998, and was on active duty from 1958-1960 and 1974-1998.[citation needed]
Along with Seymour Kaufman he discovered the role of ascorbic acid in the enzymatic hydroxylation of dopamine to form norepinephrine, the first evidence for a specific metabolic function for this vitamin[3]
Fellowship with Konrad Bloch at Harvard University 1961-1963, under the auspices of Sinai Hospital.[citation needed]
He was on the Faculty of Pediatrics at Johns Hopkins School of Medicine 1963-1974.[4]
Along with Vagn Flyger, he demonstrated the partial deficiency of uroporphyrinogen cosynthetase in congenital erythropoietic porphyria of cattle and human beings, its occurrence in asymptomatic carriers of the disease, in fibroblasts as well as in bone marrow, and its probable cause of red bones in fox squirrels.[5][6]
He once beat Solomon Golumb in a chess game.[citation needed]
Personal life[edit]
He married Ruth Lee Shefferman on June 17, 1956 and had four children: Joshua, Rebecca, Daniel, and Michael.[citation needed]
References[edit]
- ^ "Ephraim Levin". Washington Jewish Week. 2020-12-02. Retrieved 2021-01-20.[dead link]
- ^ "Ephraim Levin". Sagel Bloomfield Danzansky Goldberg Funeral Care Inc. Retrieved 12 August 2021.
- ^ LEVIN, EY; LEVENBERG, B; KAUFMAN, S (July 1960). "The enzymatic conversion of 3,4-dihydroxyphenylethylamine to norepinephrine". The Journal of Biological Chemistry. 235 (7): 2080–6. doi:10.1016/S0021-9258(18)69366-4. PMID 14416204.
- ^ Johns Hopkins University, Programs in Human Genetics https://profiles.nlm.nih.gov/JQ/B/B/J/C/_/jqbbjc.pdf
- ^ Levin, Ephraim Y.; Flyger, Vagn (October 1971). "Uroporphyrinogen III Cosynthetase Activity in the Fox Squirrel ( Sciurus niger )". Science. 174 (4004): 59–60. doi:10.1126/science.174.4004.59. PMID 5120867. S2CID 26381717.
- ^ Romeo, Giovanni; Levin, Ephraim Y. (July 1969). "Uroporphyrinogen III Cosynthetase in Human Congenital Erythropoietic Porphyria". Proceedings of the National Academy of Sciences. 63 (3): 856–863. doi:10.1073/pnas.63.3.856. PMC 223531. PMID 5259767.