Cynthia Reinhart-King
Cynthia A. Reinhart-King | |
|---|---|
| Alma mater | Massachusetts Institute of Technology University of Pennsylvania |
| Scientific career | |
| Institutions | University of Rochester Vanderbilt University Cornell University |
| Thesis | Traction forces exerted by endothelial cells on deformable substrates (2006) |
Cynthia "Cindy" Reinhart-King is an American biomedical engineer who is a University Distinguished Professor at Vanderbilt University. Her research considers cell motility and adhesion. She serves as president of the Biomedical Engineering Society.
Early life and education[edit]
Reinhart-King studied chemical engineering and biology at Massachusetts Institute of Technology.[1] She studied integrin-mediated signalling alongside Doug Lauffenburger.[1] Integrin-mediated signalling describes the molecular signals that are initiated when an extracellular ligand binds to an integrin on the cellular surface, resulting in the regulation of a downstream cellular process. After graduating, she joined the University of Pennsylvania as a doctoral student, where she worked on cell adhesion in the endothelium.[2] She moved to the University of Rochester for postdoctoral research, studying atherosclerosis with Bradford Berk.[1]
Research and career[edit]
Reinhart-King's research has helped understanding of cancer progression.[3] She has monitored disease progression at the molecular, cellular and tissue level.[4] Her analytical strategy combines cellular imaging with mechanical measurements, histology and biochemical assays.[5] She showed how the cellular matrix stiffens after tumour formation, promoting tumour growth and impacting the effectiveness of cancer treatments.[3] Her lab have demonstrated that although cancer cells move quickly during metastasis, their migration through the body occurs via the most easy pathways.[6] In particular, they favor wider spaces that are easier navigated than smaller and more confined ones.[7]
Reinhart-King has also investigated diabetic retinopathy. This condition can cause blindness in diabetic patients.[4] She started her independent scientific career at Cornell University.[8]
In 2021, Reinhart-King became President Elect of the Biomedical Engineering Society.[9] She was made Senior Associate Dean for Research at Vanderbilt University in 2022.[10] She has been involved with science policy, serving as an expert advisor to the federal government of the United States on biotechnology and biomanufacturing.[11]
Awards and honors[edit]
- 2010 Rita Schaffer Young Investigator Award[12]
- 2011 NSF Faculty Early Career Award[13]
- 2016 Elected Fellow of the American Institute for Medical and Biological Engineering[14]
- 2017 Elected Fellow of the Biomedical Engineering Society[4]
- 2016 National Academy of Engineering Frontiers Fellow[15]
- 2018 Biomedical Engineering Society Mid-Career Award[16]
- 2018 National Academies of Sciences, Engineering, and Medicine Inaugural New Voices Fellow[3][17]
- 2019 Grace Hopper Distinguished Lecture[18]
- 2022 Elected President of the Biomedical Engineering Society[19][20]
Selected publications[edit]
- Matthew J Paszek; Nastaran Zahir; Kandice R Johnson; et al. (September 2005). "Tensional homeostasis and the malignant phenotype". Cancer Cell. 8 (3): 241–54. doi:10.1016/J.CCR.2005.08.010. ISSN 1535-6108. PMID 16169468. Wikidata Q27860932.
- Cynthia A Reinhart-King; Micah Dembo; Daniel A Hammer (5 September 2008). "Cell-cell mechanical communication through compliant substrates". Biophysical Journal. 95 (12): 6044–6051. doi:10.1529/BIOPHYSJ.107.127662. ISSN 0006-3495. PMC 2599854. PMID 18775964. Wikidata Q37008291.
- Cynthia A Reinhart-King; Micah Dembo; Daniel A Hammer (22 April 2005). "The dynamics and mechanics of endothelial cell spreading". Biophysical Journal. 89 (1): 676–689. doi:10.1529/BIOPHYSJ.104.054320. ISSN 0006-3495. PMC 1366566. PMID 15849250. Wikidata Q34350613.
Personal life[edit]
Reinhart-King is married to Michael King, the J. Lawrence Wilson Professor of Engineering at Vanderbilt University.[5][21] Together they have two children.[1]
References[edit]
- ^ a b c d "Reinhart-King Laboratory: Meet the PI". cellmechanics.org. Archived from the original on 2022-12-29. Retrieved 2022-12-29.
- ^ ksas (2021-11-04). "Penn Bioengineering Alumna Cynthia Reinhart-King is President Elect of BMES". Penn Bioengineering Blog. Archived from the original on 2022-12-29. Retrieved 2022-12-29.
- ^ a b c "Cynthia Reinhart-King to serve on National Academies inaugural New Voices panel". Vanderbilt University. Archived from the original on 2022-12-29. Retrieved 2022-12-29.
- ^ a b c "Cynthia Reinhart-King named Biomedical Engineering Society Fellow". Vanderbilt University. Archived from the original on 2022-12-29. Retrieved 2022-12-29.
- ^ a b "Bio". School of Engineering. Retrieved 2022-12-29.
- ^ "Like racecars and geese, cancer cells draft their way to new tumor sites". Vanderbilt University. 2019-03-25. Archived from the original on 2022-12-29. Retrieved 2022-12-29.
- ^ ""Lazy" Cancer Cells Choose the Path of Least Resistance". Cancer Research from Technology Networks. Archived from the original on 2022-12-29. Retrieved 2022-12-29.
- ^ "Cynthia Reinhart-King | Cornell's Next-Gen Leaders in the Life Sciences". CornellCast. Archived from the original on 2022-12-29. Retrieved 2022-12-29.
- ^ "Cynthia Reinhart-King is president-elect of the Biomedical Engineering Society". Vanderbilt University. Archived from the original on 2022-12-29. Retrieved 2022-12-29.
- ^ "Cynthia Reinhart-King is Senior Associate Dean for Research in School of Engineering". Vanderbilt University. Archived from the original on 2022-12-29. Retrieved 2022-12-29.
- ^ "Preeminent engineering researcher takes part in national summit on biotechnology and biomanufacturing". Vanderbilt University. 2022-09-20. Archived from the original on 2022-12-29. Retrieved 2022-12-29.
- ^ "BMES Rita Schaffer Young Investigator Award - Biomedical Engineering Society". www.bmes.org. Archived from the original on 2022-12-29. Retrieved 2022-12-29.
- ^ "NSF Award Search: Award # 1741588 - CAREER:Functional Heterogeneity in Cell Chemotaxis". nsf.gov. Archived from the original on 2022-12-29. Retrieved 2022-12-29.
- ^ "Cynthia Reinhart-King, Ph.D. COF-2039 - AIMBE". Archived from the original on 2022-12-29. Retrieved 2022-12-29.
- ^ Engineering, National Academy of (2017-01-31). Frontiers of Engineering: Reports on Leading-Edge Engineering from the 2016 Symposium. ISBN 978-0-309-45036-2. Archived from the original on 2022-12-29. Retrieved 2022-12-29.
- ^ "BMES Mid-Career Award - Biomedical Engineering Society". www.bmes.org. Archived from the original on 2022-12-29. Retrieved 2022-12-29.
- ^ "Cynthia Reinhart-King Cynthia Reinhart-King to serve on National Academies inaugural New Voices panel - AIMBE". Archived from the original on 2022-12-29. Retrieved 2022-12-29.
- ^ "Grace Hopper Lecture". Archived from the original on 2022-12-29. Retrieved 2022-12-29.
- ^ "Cynthia A Reinhart-King - Biomedical Engineering Society". www.bmes.org. Archived from the original on 2022-10-25. Retrieved 2022-12-29.
- ^ "Two Vanderbilt biomedical engineers lead top academic societies in their fields". Vanderbilt University. Archived from the original on 2022-12-29. Retrieved 2022-12-29.
- ^ "A delicate balance: work and family". ezramagazine.cornell.edu. Archived from the original on 2022-10-25. Retrieved 2022-12-29.
| Authority control databases: Academics |
|---|
- Living people
- American biomedical engineers
- 21st-century American engineers
- 21st-century American women engineers
- Massachusetts Institute of Technology alumni
- University of Pennsylvania alumni
- University of Rochester alumni
- Cornell University faculty
- Vanderbilt University faculty
- Fellows of the American Institute for Medical and Biological Engineering
- Fellows of the Biomedical Engineering Society