DHH phosphatase family
| DHH family | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 streptococcus mutans inorganic pyrophosphatase | |||||||||
| Identifiers | |||||||||
| Symbol | DHH | ||||||||
| Pfam | PF01368 | ||||||||
| InterPro | IPR001667 | ||||||||
| SCOP2 | 1i74 / SCOPe / SUPFAM | ||||||||
| |||||||||
In molecular biology, the DHH phosphatase family is a family of putative phosphoesterases. The family includes Drosophila prune protein and bacterial RecJ exonuclease.[1] The RecJ protein of Escherichia coli plays an important role in a number of DNA repair and recombination pathways. RecJ catalyses processive degradation of single-stranded DNA in a 5'-to-3' direction. Sequences highly related to those encoding RecJ can be found in many of the eubacterial genomes sequenced to date.[2]
References[edit]
- ^ Aravind L, Koonin EV (January 1998). "A novel family of predicted phosphoesterases includes Drosophila prune protein and bacterial RecJ exonuclease". Trends in Biochemical Sciences. 23 (1): 17–9. doi:10.1016/s0968-0004(97)01162-6. PMID 9478130.
- ^ Rajman LA, Lovett ST (February 2000). "A thermostable single-strand DNase from Methanococcus jannaschii related to the RecJ recombination and repair exonuclease from Escherichia coli". Journal of Bacteriology. 182 (3): 607–12. doi:10.1128/jb.182.3.607-612.2000. PMC 94321. PMID 10633092.