Barbara S. Larsen

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Barbara Seliger Larsen
Alma materSanta Clara University(BS)
University of Delaware(PhD)
AwardsDuPont Pederson Medal (2015)
Eastern Analytical Symposium (EAS) Award for Outstanding Achievements in Mass Spectrometry(2020)
Scientific career
FieldsChemistry
InstitutionsDuPont
ThesisStructure and energetics of metal containing ions : ion cyclotron resonance and collision induced decomposition mass spectrometric studies (1983)
Doctoral advisorDouglas P. Ridge

Barbara Seliger Larsen is a mass spectrometrist, with a career in instrumentations and applications of mass spectrometry in industry, and served on the board of the American Society for Mass Spectrometry for several terms.[1]

Early life and education[edit]

Larsen earned a BS in chemistry from Santa Clara University in 1978, and a PhD in chemistry under the direction of Douglas P. Ridge from University of Delaware in 1983.[2] She completed her post-doctoral research with Catherine Fenselau at Johns Hopkins University.[1]

Career[edit]

Larsen worked for more than 35 years at DuPont.[3] In her research in mass spectrometry, she worked with a number of ionization sources, from electrospray ionization,[4][5] matrix-assisted laser desorption/ionization,[6] solid probe introduction with corona discharge ionization,[7] to laserspray ionization.[8] Her fluorinated polymer extraction method,[9][10] the Larsen method, is required by the Environmental Protection Agency for consumer safety.[11] She is a consultant at Larsen Scientific Consulting.[12]

She serves on the editorial advisory board of Spectroscopy.[12] She was an editor for the Journal of the American Society for Mass Spectrometry.[13] She served on a number of board positions for the American Society for Mass Spectrometry: treasurer (1992-1994), vice president for programs (2004-2006), president (2006-2008), and past president (2008-2010).[14][15] She was elected as an American Chemical Society Fellow in 2017.[16]

Honors and awards[edit]

  • 2010 American Chemical Society The Delaware Section Award[17]
  • 2015 Dupont Pederson Medal[18]
  • 2016 the Analytical Scientist The Power List 2016 Top 50 most influential women[19]
  • 2020 Eastern Analytical Symposium (EAS) Award for Outstanding Achievements in Mass Spectrometry[20]

Books and book chapters[edit]

Books

  • Fulton G. Kitson; Barbara S. Larsen, Charles N. McEwen (1996) Gas Chromatography and Mass Spectrometry: A Practical Guide Academic Press.[21]
  • Barbara S. Larsen; Charles N. McEwen (Eds.) (2014) Mass Spectrometry of Biological Materials. 2nd Edition. CRC Press.[2]

Book chapters

  • Charles N. McEwen; Barbara S. Larsen (1997) Electrospray ionization on quadrupole and magnetic-sector mass spectrometers, in Electrospray ionization mass spectrometry: fundamentals, instrumentation, and applications. Richard B. Cole (Ed.) Wiley. 177–202.[22]
  • Sarah Trimpin; David E. Clemmer; Barbara S. Larsen (2010) Snapshot, Conformation, and Bulk Fragmentation of Polymeric Architectures using ESI–IMS–MS, in Ion Mobility Spectrometry–Mass Spectrometry: Theory and Applications. CRC Press. 215–235.[23]

References[edit]

  1. ^ a b Brenner, Anne; Simpson, Hayes (2021-09-01). "Faces of Mass Spectrometry/Barbara Larsen". Journal of the American Society for Mass Spectrometry. 32 (9): 2281–2283. doi:10.1021/jasms.1c00229. ISSN 1044-0305. PMID 34375110. S2CID 236978779.
  2. ^ a b Mass spectrometry of biological materials. Barbara Seliger Larsen, Charles N. McEwen (2nd ed., rev. and expanded ed.). New York: Marcel Dekker. 1998. ISBN 0-585-11050-6. OCLC 44959064.{{cite book}}: CS1 maint: others (link)
  3. ^ "Barbara Larsen Receives EAS Award for Outstanding Achievements in Mass Spectrometry". Spectroscopy Online. 30 September 2020. Retrieved 2022-06-08.
  4. ^ Larsen, Barbara S.; McEwen, Charles N. (1991-05-01). "An electrospray ion source for magnetic sector mass spectrometers". Journal of the American Society for Mass Spectrometry. 2 (3): 205–211. doi:10.1016/1044-0305(91)80045-9. ISSN 1044-0305. PMID 24242274. S2CID 40950182.
  5. ^ McEwen, Charles N.; Simonsick, William J.; Larsen, Barbara S.; Ute, Kaichi; Hatada, Koichi (1995-10-01). "The fundamentals of applying electrospray ionization mass spectrometry to low mass poly(methyl methacrylate) polymers". Journal of the American Society for Mass Spectrometry. 6 (10): 906–911. doi:10.1016/1044-0305(95)00476-T. ISSN 1044-0305. PMID 24214034. S2CID 21026081.
  6. ^ McEwen, Charles N.; Jackson, Christian; Larsen, Barbara S. (1997). "Instrumental effects in the analysis of polymers of wide polydispersity by MALDI mass spectrometry". International Journal of Mass Spectrometry and Ion Processes. 160 (1–3): 387–394. Bibcode:1997IJMSI.160..387M. doi:10.1016/S0168-1176(96)04501-6.
  7. ^ McEwen, Charles N.; McKay, Richard G.; Larsen, Barbara S. (2005-12-01). "Analysis of Solids, Liquids, and Biological Tissues Using Solids Probe Introduction at Atmospheric Pressure on Commercial LC/MS Instruments". Analytical Chemistry. 77 (23): 7826–7831. doi:10.1021/ac051470k. ISSN 0003-2700. PMID 16316194.
  8. ^ McEwen, Charles N.; Larsen, Barbara S.; Trimpin, Sarah (2010-06-15). "Laserspray Ionization on a Commercial Atmospheric Pressure-MALDI Mass Spectrometer Ion Source: Selecting Singly or Multiply Charged Ions". Analytical Chemistry. 82 (12): 4998–5001. doi:10.1021/ac1006624. ISSN 0003-2700. PMID 20469839.
  9. ^ Larsen, Barbara S.; Kaiser, Mary A.; Botelho, Miguel; Wooler, Gilbert R.; Buxton, L. William (2005). "Comparison of pressurized solvent and reflux extraction methods for the determination of perfluorooctanoic acid in polytetrafluoroethylene polymers using LC-MS-MS". The Analyst. 130 (1): 59–62. Bibcode:2005Ana...130...59L. doi:10.1039/b412609b. ISSN 0003-2654. PMID 15614354.
  10. ^ Larsen, Barbara S.; Kaiser, Mary A.; Botelho, Miguel A.; Bachmura, Stanley F.; Buxton, L. William (2006). "Efficient "total" extraction of perfluorooctanoate from polytetrafluoroethylene fluoropolymer". The Analyst. 131 (10): 1105–1108. Bibcode:2006Ana...131.1105L. doi:10.1039/B606801D. ISSN 0003-2654. PMID 17003857.
  11. ^ "News and Views" (PDF). American Society for Mass Spectrometry. 2017. Retrieved 2022-06-08.
  12. ^ a b "Spectroscopy Editorial Advisory Board". Spectroscopy Online. January 2019. Retrieved 2022-06-08.
  13. ^ "Journal of The American Society for Mass Spectrometry". Springer. December 2019. Retrieved 2022-06-08.
  14. ^ "Past Presidents". www.asms.org. Retrieved 2022-06-08.
  15. ^ "ASMS Board of Directors History" (PDF). American Society for Mass Spectrometry. Retrieved 2022-06-07.
  16. ^ "Seven Division Members Elected as American Chemical Society Fellows". ACS Division of Analytical Chemistry. 2017-06-22. Retrieved 2022-06-08.
  17. ^ "Awards | ACS | Delaware Section". delawareacs.org. Retrieved 2022-06-08.
  18. ^ "Barbara S. Larsen Awarded DuPont Pederson Medal". www.asms.org. Retrieved 2022-06-08.
  19. ^ "The Power List 2016". The Analytical Scientist. Retrieved 2022-06-08.
  20. ^ "59th Eastern Analytical Symposium November 16–19, 2020". Spectroscopy Online. 7 September 2020. Retrieved 2022-06-08.
  21. ^ Kitson, Fulton G. (1996). Gas chromatography and mass spectrometry : a practical guide. Barbara Seliger Larsen, Charles N. McEwen. San Diego, Calif.: Academic Press. ISBN 978-0-08-053232-5. OCLC 173649318.
  22. ^ Electrospray ionization mass spectrometry : fundamentals, instrumentation, and applications. Richard B. Cole. New York: Wiley. 1997. ISBN 0-471-14564-5. OCLC 35637508.{{cite book}}: CS1 maint: others (link)
  23. ^ Wilkins, Charles L.; Trimpin, Sarah, eds. (2011), "Snapshot, Conformation, and Bulk Fragmentation Characterization of Polymeric Architectures Using ESI-IMS-MS", Ion Mobility Spectrometry - Mass Spectrometry, CRC Press, doi:10.1201/b10460-17, ISBN 978-0-429-13427-2, retrieved 2022-06-08
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