Subareolar lymphatic plexus
Subareolar lymphatic plexus, also known as Sappey's plexus is the lympatic drainage of the areola of the breast.[1] It is a dense network of lympatics located in the dermis.[2] The subareolar plexus of Sappey communicated with the plexus of lymph nodes located in the deep fascia of pectoralis major muscle.[3]
Clinical significance[edit]
Subareoloar lympatic plexus is involved in the axillary spread of breast cancer to the surrounding organs.[3]
History[edit]
In 1874, the French anatomist Marie Philibert Constant Sappey discovered the subareoloar lympatic plexus by injecting mercury into the dermis of the breast of a cadaver. Sappey's description became the theoritical basis for subareolar injection for lympatic mapping of the breast.[2]
References[edit]
- ^ Fregnani, Jose. "Lymphatic drainage of the breast: From theory to surgical practice" (PDF). International Journal of Morphology. Retrieved 28 July 2023.
- ^ a b Suami, Hiroo; Pan, Wei-Ren; Mann, G. Bruce; Taylor, G. Ian (1 March 2008). "The Lymphatic Anatomy of the Breast and its Implications for Sentinel Lymph Node Biopsy: A Human Cadaver Study". Annals of Surgical Oncology. 15 (3): 863–871. doi:10.1245/s10434-007-9709-9. ISSN 1534-4681. PMC 2234450. PMID 18043970.
- ^ a b Rasool, Zahida; Hassan, Ashfaq Ul; Hassan, Ghulam; Masood, Tanveer (July 2013). "Importance of lymphatic's in dissemination of breast cancer-Anatomical, pathological, surgical and prognostic implications". International Journal of Anatomy Research. Retrieved 28 July 2023.