Placental site nodule
| Placental site nodule | |
|---|---|
 | |
| Micrograph of a placental site nodule (top of image). H&E stain. |
A placental site nodule (PSN) is benign remnant from a previous pregnancy.[1]
Presentation[edit]
They are typically asymptomatic and found incidentally.[1]
Pathology[edit]
PSNs are intermediate trophoblastic remnants.
Diagnosis[edit]
PSNs are diagnosed by examining the tissue under a microscope, usually obtained with a dilation and curettage.
Typically, they consist of pink (hyaline) material using the standard stain and contain few cells. Bizarre multinucleated cells may be present; however, there is no mitotic activity. The differential diagnosis includes (cervical) squamous cell carcinoma, gestational trophoblastic disease, and exaggerated placental site.
Prognosis[edit]
PSN are benign. Once removed, they do not require any treatment and do not recur.
See also[edit]
References[edit]
- ^ a b Jacob, S.; Mohapatra, D. (2009). "Placental site nodule: a tumor-like trophoblastic lesion". Indian J Pathol Microbiol. 52 (2): 240–1. doi:10.4103/0377-4929.48931. PMID 19332926.